RESEARCH DESIGN AND METHODS —History and laboratory data, including islet-related autoantibodies, were examined in 222 patients with fulminant and nonfulminant type 1 diabetes in our hospitals in addition … From epidemiologic perspectives in Asia based on acase report, there are 20% of fulminant type 1 diabetes case amongst all of type 1 diabetes cases in Japan. Shuoming Luo and Zhenyi Zhang contributed equally to this work. Case Report. Fulminant type 1 diabetes is associated with pregnancy. IA-2A. ZnT8A. However, the association between fulminant type 1 diabetes in pregnancy and specific viral infections has not been reported.
Fulminant type 1 diabetes appears to a disease subtype that features a characteristic range of clinical symptoms, with extremely rapid onset, and thus must be treated very quickly. OBJECTIVE — To describe the clinical and immunologic characteristics of fulminant type 1 diabetes, a novel subtype of type 1 diabetes, we conducted a nationwide survey. Fulminant type 1 diabetes that was not associated with pregnancy. This is a preview of subscription content, log in to check access. Type 1 diabetes is now defined as "diabetes characterized by β-cell destruction, usually leading to absolute insulin deficiency" by the American Diabetes Association, the World Health Organization and the Japan Diabetes Society [1-3].In this context, fulminant type 1 diabetes is a typical type 1 diabetes characterized by its clinical features of abrupt onset with ketosis … Autoantibodies against glutamic acid decarboxylase.
Fulminant type 1 diabetes differs from type 1A diabetes in which it will take years to develop autoantibodies to the clinical onset of ketosis or ketoacidosis. Protein tyrosine phosphatase autoantibodies. Testing revealed very high levels of blood glucose (86.9 mmol/l), urinary glucose (2+) and ketones (4+). In the 2 patient cases described in this study, gastrointestinal symptoms were the first symptoms reported, and … Fulminant type 1 diabetes is characterized by an intrinsic insulin deficiency resulting from the severe destruction of pancreatic β cells and it rapidly leads to ketoacidosis. A total of 24 patients with fulminant T1DM and 48 classical autoimmune T1DM patients with acute onset of ketoacidosis were recruited. However, the patient then went into cardiopulmonary arrest, and was transferred to our hospital for treatment. ICA. Introduction.
This study aimed at examining the clinical and autoimmunity features of fulminant T1DM in Chinese. This means that while infection with one specific virus does not cause fulminant type 1 diabetes, several viruses possibly contribute to the onset of fulminant type 1 diabetes. Autoantibodies against islet cells. Fulminant type 1 diabetes is defined as a subtype of type 1 diabetes with a remarkably acute onset. Fulminant type 1 diabetes mellitus (T1DM) is characterized by abrupt onset of hyperglycemia and rapid progression to ketoacidosis.
Methods. Citing Literature. We describe herein the case of a woman who developed fulminant type 1 diabetes during anti‐PD‐1 therapy, with some important findings that should contribute to elucidation of the pathogenesis. As previously reported using a candidate gene approach, a strong association was observed with multiple single nucleotide polymorphisms (SNPs) in the HLA region, and the strongest association was observed with rs9268853 in the class II DR region ( P = 1.56 × 10−23, odds ratio [OR] …
The first genome-wide association study of fulminant type 1 diabetes was performed in Japanese individuals. Zinc transporter 8 autoantibodies. GADA.
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